In plant genomes, histone H1 and DNA methylation cooperatively silence transposable elements, silence intragenic antisense transcripts, as well as maintain…
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UBE3A encodes E3 ubiquitin ligase and regulates brain’s immune system, which is associated with Angelman syndrome. More: UBE3A regulates the…
Out of 295 yeast strains, each with deleted single intron, 64% do not survive stress conditions. Their function in stress…
Enhancer specific for cell type helps to form pre-initiation complex – in a manner of burst frequency, stimulates expression of…
LINE-1 becomes active shortly after fertilization, which was observed by expression measurements, as well as sequencing of embryos. More: LINE-1…
Human genome from 70th to 80th year of life, becomes globally more disrupted, with evident changes in genetic control, genes…
Some scientists criticize polygenic risk scores, such as those assessing the risk of coronary artery disease, because of their low…
Mutations lower survival of cancer cells, but at the same time they utilize Eukaryotic Mutation Burden Response. More: A stress…
Interactions between distinct chromosomes and various fragments of the same chromosomes have been showed to play an important role in…
A protein complex have been found to change specific mechanism of gene regulation (recursive splicing) in human brain cells. Humans…