How the human genome changes after 10 years of ageing?

Human genome from 70th to 80th year of life, becomes globally more disrupted, with evident changes in genetic control, genes governing sleep/wake cycle, immune response genes, as well as DNA repair genes.

More: Genetic dysregulation of gene expression and splicing during a ten-year period of human aging, B. Balliu et al., posted at bioRxiv 13th January 2019, doi:10.1101/519520 – not peer-reviewed