Human embryo genome undergoes modifications from the very beginning

LINE-1 becomes active shortly after fertilization, which was observed by expression measurements, as well as sequencing of embryos.

More: LINE-1 retrotransposition impacts the genome of human pre implantation embryos and extraembryonic tissues, M. Munoz-Lopez et al., posted 18th January 2019 at bioRxiv, doi:10.1101/522623 – not peer-reviewed