The largest catalogue of cancer mutations – COSMIC

A new version of COSMIC (Catalogue Of Somatic Mutations In Cancer) is available under https://cancer.sanger.ac.uk/cosmic.

2018 v86 relase of the catalogue describes 719 genes in the context of all cancer types.

Additionaly, there were listed 145 genes recently linked with tumors but without detailed mechanism explained by current scientific research.

The review provides comprehensive synthesis of modern knowledge about genetics of cancer.

More: “The COSMIC Cancer Gene Census: describing genetic dysfunction across all human cancers”, Z. Sondka et al., 2018, doi:10.1038/s41568-018-0060-1.